An Overview on Gastroretentive Drug Delivery System: Current Approaches and Advancements

  • Anu Tomar Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology (MIET), NH-58, Delhi-Roorkee Highway, Meerut-250005, Uttar Pradesh, India
  • Aakash Upadhyay Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology (MIET), NH-58, Delhi-Roorkee Highway, Meerut-250005, Uttar Pradesh, India
  • S K Gupta Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology (MIET), NH-58, Delhi-Roorkee Highway, Meerut-250005, Uttar Pradesh, India
  • Shobhit Kumar Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology (MIET), NH-58, Delhi-Roorkee Highway, Meerut-250005, Uttar Pradesh, India

Abstract

Gastroretentive Drug Delivery System (GRDDS) can elevate the controlled delivery of drugs that have an absorption window by continuously releasing the drug for a constant period of time before it extends its absorption site. This includes floating system, dilation and expanding system, muco - adhesive system, high density system and other postponed gastric emptying devices. The present article briefly about the formulation consideration for GRDDS, factors controlling gastric retention time, advantages, disadvantages and evaluation of GRDDS.

Keywords: Gastroretentive drug delivery system, floating system, non floating system

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How to Cite
Tomar, A., A. Upadhyay, S. K. Gupta, and S. Kumar. “An Overview on Gastroretentive Drug Delivery System: Current Approaches and Advancements”. Current Research in Pharmaceutical Sciences, Vol. 9, no. 1, Apr. 2019, pp. 12-16, doi:10.24092/CRPS.2019.090102.
Section
Review Articles