Synthesis and Antimicrobial activity Of Some New Thiosemicarbazones
Abstract
Some new [ 5-mercapto-3-(p-nitrophenyl)-4-amino substituted-1,2,4-triazole] thiosemicarbazones were synthesized in microwave and there structures were confirmed by I.R. and 1H NMR and their antimicrobial screening against E. Coli , Staphylococcus aureus and Candida albicans were established by zone of inhibition.
Keywords:
thiosemicarbazones, zones of inhibition, antimicrobial activity.
References
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2. Perumal Y, Sriram D. Stables James. Eur. J. Med. Chem. 2002;37:231.
3. Hussain A., Sharba K., Al-Bayati R. H., Aouad M., Rezki N., Molecules,10,1161 (2005).
4. Wujec M, Pitucha M, Dobosz M. Kosikowska Urszula, Malm Anna. Acta Pharma. 2004;54:251.
5. Baluza S, Chanda S, Chabhadiya R, Kachhadia N, Nair R, Solanki A. J. Serb. Chem. Soc.2007; 72(6): 539.
6. Colanceska RK, Dimova V, Kakurinov V, Molnar DG, Buzarovaska A. Molecules.2001; 6:815.
7. Cansiz A, Koparir M, Damirdag A. Molecules. 2004; 9: 204.
8. Yogeeswari P, Sriram D, Mehta S, Nigam D, Kumar MM, Murugesan S. J.P.Stables. IL FARMACO. 2005; 60:1.
9. Kudari SM, Lagali KH. Ind.J.Chem.1993; 32B:379.
10. Desai KG, Desai KR. Ind.J.Chem.2005;44B: 97.
11. Reid JR, Heindel ND. J. Heterocyclic Chem. 1976;13:925.
12. Naik B, Desai KR. Ind.J.Chem. 2006; 45B: 267.
13. Panwar H, Verma RS,Srivastava VK, Kumar A. Ind.J.Chem.2006;45B:2099.
14. Pandeya SN, Yogeeswari P, Stables James P. Eur. J. Med. Chem. 2000 ;35 :879.
15. Yogeeswari P, Thirumurugan R, Kavya R, Samuel S, Stables J, Sriram D. Eur. J. Med. Chem. 2004 ;39 :729.
16. Zamani K, Faghihi K, Sangi MR, Zolgharnein J.Turk. J. Chem. 2003 ;27 :119.
17. Demirbas N, Demirbas A, Sancak K. Eur. J. Med. Chem. 2004; 39:793.
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How to Cite
Tyagi, A. M., M. P. Toraskar, and V. J. Kadam. “Synthesis and Antimicrobial Activity Of Some New Thiosemicarbazones”. Current Research in Pharmaceutical Sciences, Vol. 1, no. 1, Dec. 2011, pp. 20-24, https://crpsonline.com/index.php/crps/article/view/33.
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