Clinical Trials

  • Narendra Prajapati Shri Guru Ram Rai Institute of Pharmacy, Dehradun.
  • Megha Gupta Shri Guru Ram Rai Institute of Pharmacy, Dehradun.
  • Yusra Ahmad Shri Guru Ram Rai Institute of Pharmacy, Dehradun.


A clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known treatments. Clinical Trials also called medical research and research studies] are used to determine whether new drugs or treatments are both safe and effective. Carefully conducted clinical trials are the fastest and safest way to find treatments that work. Leads for clinical trials usually come from researchers. Once researchers test new therapies or procedures in the laboratory [animal studies] and get promising results, they begin planning Phase I clinical trials [in humans].New therapies are tested on people only after laboratory and animal studies show promising results. Clinical Trials make it possible to apply the latest scientific and technological advances to patient care. When a new medical treatment is studied for the first time in humans, it is not known exactly how it will work. With any new treatment, there are possible risks as well as benefits

Keywords: Medical Research, Vaccines, Therapies, Phase I, Scientific.


1. Avorn J. Powerful Medicines. (2004) 129-133.
2. Van Spall HG, Toren A, Kiss A, Fowler RA. Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review. JAMA. 2007; 11:1233–40.
3. The regulatory authority in the USA is the Food and Drug Administration; in Canada, Health Canada; in the European Union, the European Medicines Agency; and in Japan, the Ministry of Health, Labour and Welfare
4. Green J, Benedetti J. Clinical Trials Handbook. Shayne Cox Gad. John Wiley and Sons. (2009) 118. 5. Curtis L, Meinert ST. Clinical trials: design, conduct, and analysis. Oxford University Press, USA (1986).
6. Toby EH. The Rise of Early Modern Science. Cambridge University Press, Islam, China and the West (2003) 218.
7. Tschanz DW. The Arab Roots of European Medicine. Saudi Aramco World. 1997; 48 (3): 20–31.
8. Craig BD, Daly WJ.Clinical pharmacology in the Middle Ages: Principles that presage the 21st century, Clinical Pharmacology & Therapeutics.2000; 67 (5): 447-450.
9. Poole AV, Peterson AM. Pharmacotherapeutics for Advanced Practice: A Practical Approach. Lippincott Williams & Wilkins(2005).
10. Crossley MJ, Turner P, Thordarson P.Clinical Trials – ―What Your Need to Know". American Cancer Society. 2007; 129 (22):7155.
11. Rang HP, Dale MM, Ritter JM, Moore PK. Pharmacology 5 ed. Edinburgh: Churchill Livingstone (2003).
12. Finn R. Cancer Clinical Trials: Experimental Treatments and How They Can Help You., Sebastopol: O'Reilly & Associates (1999).
13. Chow SC and Liu JP. Design and Analysis of Clinical Trials : Concepts and Methodologies(2004). 14. Pocock SJ. Clinical Trials: A Practical Approach, John Wiley & Sons (2004).
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How to Cite
Prajapati, N., M. Gupta, and Y. Ahmad. “Clinical Trials”. Current Research in Pharmaceutical Sciences, Vol. 1, no. 1, Dec. 2011, pp. 7-11,
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