Pharmacological Investigations of Cyperus rotundus Tuber Extract in Monosodium Glutamate Induced Experimental Animal

  • Munesh Kumar Faculty of Pharmacy IFTM University, Moradabad Uttar Pradesh-244102, India
  • Manisha Rani Faculty of Pharmacy IFTM University, Moradabad Uttar Pradesh-244102, India
  • Bibekananda Meher Columbia Institute of Pharmacy, Raipur, Chhattisgarh: 493111, India


Nowadays obesity is the major health problem due to food habit and life style of people. Nature and natural compounds possess lots of health benefits. To explore the therapeutic benefit of Cyperus rotundus in this work, we have evaluated the anti-obesity potential on Monosodium glutamate (MSG) induced obese rats. Methanolic extract of tubers of Cyperus rotundus was administered at the dose of 250 and 500 mg/kg/oral after 45 d of treatment and a significant improvement in body weight, organs and lipid profile was observed as compared with MSG induced obese rats. Nowadays obesity is a common metabolic disorder in developed and developing countries. It was observed that Cyperus rotundus tuber possesses anti-obesity potential and protective action on heart and liver.

Keywords: Cyperus rotundus, obesity, Monosodium glutamate, Lipid profile, Orlistat


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How to Cite
Munesh Kumar, Manisha Rani, and Bibekananda Meher. “Pharmacological Investigations of Cyperus Rotundus Tuber Extract in Monosodium Glutamate Induced Experimental Animal”. Current Research in Pharmaceutical Sciences, Vol. 10, no. 1, May 2020, pp. 06-12, doi:10.24092/CRPS.2020.100102.
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