Transferosome: A Suitable Delivery System for Percutaneous Administration

  • Lovely Chaurasia Department of Pharmaceutics, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005
  • Sumita Singh Department of Pharmaceutics, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005
  • Kunal Arora Department of Pharmaceutics, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005
  • Charu Saxena Department of Pharmaceutics, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005

Abstract

In pharmaceutical research, the percutaneous route of drug has gained a great interest. Percutaneous delivery has enhanced a noval vesicular drug carrier system called transferosome introduced in 1990, which is composed of water, surfactant and phospholipid. The elasticity of vesicular transferosome is more than the standard liposome therefore well suited for the penetration into the skin. The transferosomes can be prepared by Reverse Phase Evaporation method, Modified Hand Shaking, Lipid Film Hydration Technique and Thin Film Hydration Technique. This article is focused on various drug lists which easily accommodate in transferosome. Transferosome application areas included Delivery of Insulin, Carrier for Interferons and Interlukin, Transdermal Immunization, and Carrier for Other Proteins and Peptides, Peripheral Drug Targeting, Transdermal Immunization, Delivery of NSAID, and Delivery of steroidal hormones etc. To overcome problems of systemic toxicity associated with targeting therpy, enhance treatment resolution of targeting therapies.

Keywords: Percutaneous, Transferosome, Carrier, Delivery, Targeting therpy

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How to Cite
Chaurasia, L., S. Singh, K. Arora, and C. Saxena. “Transferosome: A Suitable Delivery System for Percutaneous Administration”. Current Research in Pharmaceutical Sciences, Vol. 9, no. 1, Apr. 2019, pp. 1-11, doi:10.24092/CRPS.2019.090101.
Section
Review Articles