Hepatoprotective Activity of Ficus religiosa Leaf Extract in Rats

  • Archna Selvan RKDF College of Nursing, Bhopal (MP), India
  • Vivek Chourasia RKDF College of Pharmacy, Bhopal (MP), India

Abstract

Ficus religiosa was investigated for its possible protective effect against paracetamol and CCl4-induced hepatic damage. IV administration of a sub-lethal dose of paracetamol (500 mg/kg) produced liver damage in rats as manifested by the rise in serum level of transaminases (AST and ALT). Ttreatment of rats with Ficus religiosa(200 mg/kg) prevented the paracetamol-induced rise in serum enzymes. The hepatotoxic dose of CCl4 (1.5 ml/kg; orally) also raised the serum AST and ALT levels. The same dose of Ficus religiosa(200 mg/kg) was able to prevent the CCl4-induced rise in serum enzymes. These results indicate that Ficus religiosa possesses hepatoprotective activity. 

Keywords: Ficus religiosa, paracetamol, CCl4, Hepatoprotective.

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How to Cite
Selvan, A., and V. Chourasia. “Hepatoprotective Activity of Ficus Religiosa Leaf Extract in Rats”. Current Research in Pharmaceutical Sciences, Vol. 7, no. 2, July 2017, pp. 64-68, doi:10.24092/CRPS.2017.070205.
Section
Research Articles